The Berlin Patient Timothy Ray Brown - 1431 Words

The Berlin Patient Timothy Ray Brown, gained his title as â€Å"The Berlin Patient† after being the first man successfully cured of HIV (human immunodeficiency virus) in 2008, Berlin. Brown has been battling with HIV for 11 years with antiretroviral drugs since 1995 when he was diagnosed. Then in 2006, he was being diagnosed with acute myeloid leukemia, another disease that would put his life in danger. Acute myeloid leukemia is a type of cancer that attacks the bone marrow and spread to blood.[9] To treat his new deadly disease, Brown has tried radiation and chemotherapy which both did not seem to be successful in helping him. In 2007 and 2008 he made the decision of going for a bone marrow transplant. Brown’s oncologist has chose a bone marrow donor with a genetic mutation known as delta 32 which is found in 1 to 2 percent of the people in Northern Europe. For people with the delta 32 mutation, they are very likely to be immune to Smallpox, the Bubonic Plague and resistant to HIV and A IDS. [10] Focusing on how HIV is prevented by this mutation, HIV virus usually enters a cell through the cell’s CCR5 receptor and fuse into the cell that will eventually divide itself and spread throughout the patient’s body, infecting the patient with cells that is infected with HIV viruses. With the delta 32 mutation, the entry of HIV is blocked due to their misshapen CCR5 protein. Immunity to HIV is only present to homozygous carriers for the delta 32 mutation on both genes. [11] [12] TheShow MoreRelatedVaccine For Hiv Happen On The Horizon By 2030924 Words   |  4 Pageshave been documented. One case in 2007, was a turning point for HIV research. Following a bone marrow transplant of HIV sufferer â€Å"Timothy Ray Brown†. Brown underwent the procedure after he developed leukemia and the donor of the bone marrow possessed a rare genetic mutation that caused Brown cells to become resistant to HIV. Brown received the title the â€Å"Berlin Patient† in the HIV research field (defeatHIV.org) and is the first man to have been cured of the virus. In Conclusion, with the progressionRead MoreThe Human Immunodeficiency Virus : Biology, Epidemiology, And Pathogenesis3000 Words   |  12 Pageschanged the safety practices of multiple health professions including the application of Personal Protective Equipment (PPE) and the suitable training in regards to the attitude and the behavior of health professionals when dealing with HIV positive patients [40-42]. It is important to note that HIV is not transmitted by saliva, sweat, tears, mosquito bites, or water fountains [43-45]. The Human Immunodeficiency Virus shares many of its structural and biological characteristics with other viruses fromRead MoreA Research Paper About Human Immunodeficiency Virus6608 Words   |  27 PagesU.S. Centers for Disease Control (CDC) recorded a cluster of Pneumocystis cariniipneumonia  (classified as PCP) in five homosexual men in  Los Angeles and New York. These men had symptoms of a disease that now are considered typical of AIDS. In The patients were noted to have a severe reduction in a type of cell in the blood (CD4 cells) that is an important part of the immune system. These cells, often referred to as T cells, help the body fight infections. Shortly thereafter, this disease was recognizedRead MoreOne Significant Change That Has Occurred in the World Between 1900 and 2005. Explain the Impact This Change Has Made on Our Lives and Why It Is an Important Change.163893 Words   |  656 PagesEmpire produced much larger outflows. The third main producer of refugees in the post–World War II period was the spread of communism and the cold war. Two and a half million East Germans fled to West Germany between 1946 and the erection of the Berlin Wall— and many other barriers—in 1961. Many other Eastern Europeans fled westward soon after the war. More than half a million were able to flee following the Warsaw Pact put-down of the Hungarian and Czechoslovakian rebellions of 1956 and 1968Read MoreStephen P. Robbins Timothy A. Judge (2011) Organizational Behaviour 15th Edition New Jersey: Prentice Hall393164 Words   |  1573 PagesOrganizational Behavior This page intentionally left blank Organizational Behavior EDITION 15 Stephen P. Robbins —San Diego State University Timothy A. Judge —University of Notre Dame i3iEi35Bj! Boston Columbus Indianapolis New York San Francisco Upper Saddle River Amsterdam Cape Town Dubai London Madrid Milan Munich Paris Montreal Toronto Delhi Mexico City Sao Paulo Sydney Hong Kong Seoul Singapore Taipei Tokyo Editorial Director: Sally Yagan Director of Editorial Services:Read MoreDeveloping Management Skills404131 Words   |  1617 Pagesspecialties in their occupations that possess less-structured tasks. They also cope more effectively with major organizational change, downsizing, and role stress and conflict (Armstrong-Stassen, 1998; Haase, Lee, Banks, 1979; Teoh Foo, 1997; Timothy, Thoresen, Pucik, and Welbourne, 1999). It also should be pointed out, however, that individuals who are more tolerant of ambiguity have more difficulty focusing on a single important element of information—they are inclined to pay attention to a